Effects of goshuyuto on lateralization of pupillary dynamics in headache
- 作者：Akino Wakasugi ; Hiroshi Odaguchi ; Tetsuro Oikawa ; Toshihiko Hanawa
- 关键词：Kampo medicine ; Herbal medicine ; Chronic headache ; Autonomic nervous system ; Pupillary dynamics ; Iriscorder ; Laterality
- 刊名：Autonomic Neuroscience
- 出版年：2008
- 期刊代码：31_15660702
- 类别：med
- 出版时间：30 May 2008
- 卷：139
- 期：1-2
- 页码：9-14
- 文件大小：430 K
摘要
Autonomic nervous imbalance is implicated in chronic headache. We investigated the effects of goshuyuto—a representative Kampo medicine for headache—on the lateralization of the pupillary autonomic nervous system by using binocular infrared video pupillography. Patients with chronic headache were administered goshuyuto extract for 1 month (1st stage). Goshuyuto was discontinued for 1 month, following which the patients were randomly divided into 2 groups: placebo and goshuyuto. In the 2nd stage, the respective groups were administered placebo or goshuyuto for 3 months. The average laterality of the pupillary dynamics decreased significantly in the goshuyuto group.