The first examples of the enantioselective Heck-Matsuda reaction: arylation of unactivated cyclic olefins using chiral bisoxazolines

详细信息	查看全文 | 推荐本文 |

• 作者：Carlos Roque D. Correia ; ^{roque@iqm.unicamp.br} ; Caio C. Oliveira ; Airton G. Salles Jr. ; Emerson A.F. Santos
• 关键词：Enantioselective Heck&ndash ; Matsuda ; Bisoxazolines ; Arenediazonium salts
• 刊名：Tetrahedron Letters
• 出版年：2012
• 期刊代码：109_00404039
• 类别：ch
• 出版时间：27 June, 2012
• 卷：53
• 期：26
• 页码：3325-3328
• 文件大小：587 K

摘要

Successful enantioselective Heck-Matsuda arylations were accomplished for the first time using chiral bisoxazolines as ligands. Enantioselective Heck arylations were performed with several cyclic nonactivated olefins to provide the Heck products in 63-96%isolated yields and in enantiomeric excesses of 54%up to 84%.