miR-122, a paradigm for the role of microRNAs in the liver
- 作者：Muriel Girard ; Emmanuel Jacquemin ; Arnold Munnich ; Stanislas Lyonnet ; Alex ; ra Henrion-Caude
- 关键词：RNA interference ; MicroRNA ; Liver ; Metabolic disorders ; Stress ; Hepatocarcinoma ; Cholangiocarcinoma ; Viral hepatitis ; miR-122
- 刊名：Journal of Hepatology
- 出版年：2008
- 期刊代码：162_01688278
- 类别：med
- 出版时间：April 2008
- 卷：48
- 期：4
- 页码：648-656
- 文件大小：551 K
摘要
Throughout the U.S., high visibility drug markets are concentrated in neighborhoods with few economic opportunities, while drug buyers/users are widely dispersed. A study of Pittsburgh Syringe Exchange participants provides data on travel between and network linkages across neighborhoods with different levels of drug activity. There are distinct racial patterns to syringe distribution activity within networks and across neighborhoods. Pittsburgh's history suggests that these patterns emerge from historical patterns of social and economic development. Study data demonstrate the ability of IDUs to form long-term social ties across racial and geographic boundaries and use them to reduce the risk of HIV transmission.