Evaluation of antioxidant activity of Brazilian plants
- 作者：C.G. Silva ; R.S. Herdeiro ; C.J. Mathias ; A.D. Panek ; C.S. Silveira ; V.P. Rodrigues ; M.N. Rennó ; D.Q. Falcã ; o ; D.M. Cerqueira ; A.B.M. Minto et al.
- 关键词：Antioxidant activity ; Brazilian Medicinal plants ; DPPH ; Saccharomyces cerevisiae
- 刊名：Pharmacological Research
- 出版年：2005
- 期刊代码：54_10436618
- 类别：pha
- 出版时间：2005
- 卷：52
- 期：3
- 页码：229-233
- 文件大小：74 K
摘要
In this work, 22 alcoholic extracts, obtained from 14 species of plants belonging to four families, used for different food and medicinal purposes in Brazil, were evaluated for their capacity to inhibit the reduction of the free radical, 1,1-diphenyl-2-picrylhydrazyl (DPPH), and to protect Saccharomyces cerevisiae cells, an eukaryotic cell model, against the lethal oxidative stress caused by tert-butylhydroperoxide (TBH). Five extracts, two from Lamiaceae family (ethanol and butanol extracts from aerial parts of Hyptis fasciculata) and three from Palmae family (Copernicia cerifera leaves and mesocarp of fruits and the endocarp/mesocarp of fruits from Orbignya speciosa) were able to increase the tolerance of S. cerevisiae to TBH and showed to be active as DPPH radical scavengers, thus indicating that these plant extracts could be considered as potential sources of antioxidants. With the exception of ethanol extract of H. fasciculata, the remainder four extracts exhibited a DPPH radical scavenging activity higher than that obtained from Ginkgo biloba, a reference plant with well documented antioxidant activity. Interestingly, the ethanol extract of G. biloba were not effective for yeast cell protection, reinforcing the antioxidant potential of these extracts.