Traitement chirurgical des granulomes 茅osinophiles solitaires de la vo没te du cr芒ne. 脌 propos de deux cas

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• 作者：M. Berhouma^a ; ^{berhouma.moncef@yahoo.fr} ; W. Krichen^b ; A. Chamseddine^b ; H. Jemel^b
• 关键词：Eosinophilic granuloma ; Langerhans cell histiocytosis ; Bone tumor ; Cranial vault
• 刊名：Neurochirurgie
• 出版年：2009
• 期刊代码：pca376_00283770
• 类别：neu
• 出版时间：December 2009
• 卷：55
• 期：6
• 页码：555-559
• 文件大小：895 K

摘要

Langerhans cell histiocytosis is a systemic disease resulting from the oligoclonal proliferation of Langerhans cells, occurring most commonly in children and young adults. The focal form of the disease, also known as eosinophilic granuloma, most frequently involves the calvaria. We present two cases of calvarial eosinophilic granulomas that were surgically removed. These tumors are reputed to have an excellent prognosis, even if local recurrences and systemic dissemination can occur during the follow-up. The authors discuss the pathogenesis and the evolutive profile but also the therapeutic management of solitary eosinophilic granuloma of the calvaria.