Synthesis of 2,3-diaryl-5H-imidazo[2,1-a]isoindol-5-ones via the one-pot reaction of 1,2-diketones, 2-formylbenzoic acids, and ammonium acetate

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• 作者：Maryam Sadat Hosseini-Zare^a ; Mohammad Mahdavi^b ; Mina Saeedi^b ; Mehdi Asadi^b ; Shahrzad Javanshir^a ; Abbas Shafiee^b ; Alireza Foroumadi^b ; ^{aforoumadi@yahoo.com}
• 关键词：Imidazo[2 ; 1-a]isoindol-5-one ; 1 ; 2-Diketones ; Ammonium acetate
• 刊名：Tetrahedron Letters
• 出版年：2012
• 期刊代码：109_00404039
• 类别：ch
• 出版时间：4 July, 2012
• 卷：53
• 期：27
• 页码：3448-3451
• 文件大小：1148 K

摘要

We describe a new one-pot synthesis of 2,3-diaryl-5H-imidazo[2,1-a]isoindol-5-ones via the reaction of 1,2-diketones, 2-formylbenzoic acids, and ammonium acetate in acetic acid under reflux conditions and in the absence of a catalyst.