Organocatalyst trityl chloride efficiently promoted the solvent-free synthesis of 12-aryl-8,9,10,12-tetrahydrobenzo[a]-xanthen-11-ones by in situ formation of carbocationic system in neutral media

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• 作者：Ardeshir Khazaei^a ; ^{Khazaei_1326@yahoo.com} ; Mohammad Ali Zolfigol^a ; ^{mzolfigol@yahoo.com} ; ^{zolfi@basu.ac.ir} ; Ahmad Reza Moosavi-Zare^a ; Abdolkarim Zare^b ; Mahmoud Khojasteh^c ; Zhila Asgari^a ; Vahid Khakyzadeh^a ; Ali Khalafi-Nezhad^d
• 关键词：Trityl chloride ; Organocatalyst ; Multi-component reaction ; Solvent free ; 12-aryl-8 ; 9 ; 10 ; 12-tetrahydrobenzo[a]-xanthen-11-one
• 刊名：Catalysis Communications
• 出版年：2012
• 期刊代码：12_15667367
• 类别：ce
• 出版时间：5 April, 2012
• 卷：20
• 期：Complete
• 页码：54-57
• 文件大小：412 K

摘要

A highly efficient and novel procedure for the preparation of 12-aryl-8,9,10,12-tetrahydrobenzo[a]-xanthen-11-one derivatives via the one-pot three-component condensation of 2-naphthol with arylaldehydes and dimedone in the presence of catalytic amount of trityl chloride (TrCl) as a homogeneous organocatalyst under natural and solvent-free conditions is described. It is interesting that TrCl by in situ formation of trityl carbocation with inherent instability catalyzes the reaction.