Protein intake and fracture risk in elderly people: A case-control study

详细信息	查看全文 | 推荐本文 |

• 作者：Mar&iacute ; a José ; Mart&iacute ; nez-Ram&iacute ; rez^a ; ^{mjmartin@ujaen.es} ; Alberto D. Delgado-Mart&iacute ; nez^b ; ^c ; ^{adelgado@ujaen.es} ; Manuel Ruiz-Bailé ; n^d ; ^{ruizbailen@telefonica.net} ; Carmen de la Fuente^e ; ^{cfuente@unav.es} ; Miguel Á ; ngel Mart&iacute ; nez-Gonzá ; lez^e ; ^{mamartinez@unav.es} ; Miguel Delgado-Rodr&iacute ; guez^f ; ^{mdelgado@ujaen.es}
• 关键词：Osteoporosis ; Fracture risk ; Protein intake
• 刊名：Clinical Nutrition
• 出版年：2012
• 期刊代码：52_02615614
• 类别：med
• 出版时间：June, 2012
• 卷：31
• 期：3
• 页码：391-395
• 文件大小：138 K

摘要

| Figures/TablesFigures/Tables | ReferencesReferences

Summary

Background & aims

We investigated whether protein intake (PI) is related to osteoporotic fractures (OP) in the elderly by analyzing vegetable protein intake (VPI), animal protein intake (API), and animal/vegetable protein intake ratio (AVR) and by calcium intake (CaI).

Methods

A 1:1 matched by age and sex case-control study with 167 cases was carried out at the Hospital of Jaen (Spain). Cases were patients aged 鈮?5 years with a low-energy fracture. Controls were people without previous fractures. Diet was assessed by a food frequency questionnaire. Multivariable analyses were fitted using analysis of covariance (for comparison of adjusted means) and conditional logistic regression (estimating adjusted odds ratios [ORs]).

Results

The control-group showed a higher API (p聽=聽0.046) even when CaI was <800聽mg/day (p聽=聽0.041). ORs for AVR were 0.68 (0.38-1.19) and 0.38 (0.15-0.98), respectively with a p for trend聽=聽0.046. A PI<15%of the total energy intake showed an OR of 2.86 (1.10-7.43).

Conclusions

Patients with fracture history have lower API suggesting that high API reduce the occurrence of OP in elderly even if CaI is <800聽mg/day. A PI<15%of total calories were associated with an increased risk of OP in elderly.