Recurrent Mycobacterium avium infection after seven years of latency in a HIV-infected patient receiving efficient antiretroviral therapy

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• 作者：Guillaume Bussone^a ; Florence Brossier^b ; ^c ; Laurent Roudiere^a ; Emmanuelle Bille^d ; Nawal Sekkal^d ; Caroline Charlier^a ; Jacques Gilquin^a ; Fanny Lanternier^a ; Marc Lecuit^a ; Olivier Lortholary^a ; Emilie Catherinot^a ; ^e ; ^{emilie.catherinot@nck.aphp.fr}
• 关键词：Mycobacterium avium infection ; Latent infection ; HIV ; Repetitive-sequence-based polymerase chain reaction ; Bursitis
• 刊名：Journal of Infection
• 出版年：2012
• 期刊代码：6_01634453
• 类别：imm
• 出版时间：June, 2012
• 卷：64
• 期：6
• 页码：613-617
• 文件大小：437 K

摘要

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Summary

We report the first case of Mycobacterium avium reactivation, after prolonged latency, in a HIV-infected patient receiving highly active antiretroviral therapy with undetectable viral replication and normal CD4 cell count. The patient presented with a painful swollen shoulder seven years after initial M. avium bacteriaemia. Articular puncture grew M. avium. The isolates of the first and second infection were identical using repetitive-sequence-based Polymerase Chain Reaction analyses.