Integrative systems biology: an attempt to describe a simple weed

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• 作者：Louisa M Liberman¹ ; Rosangela Sozzani¹ ; Philip N Benfey ^{philip.benfey@duke.edu}
• 刊名：Current Opinion in Plant Biology
• 出版年：2012
• 期刊代码：32_13695266
• 类别：abs
• 出版时间：April, 2012
• 卷：15
• 期：2
• 页码：162-167
• 文件大小：330 K

摘要

Genome-scale studies hold great promise for revealing novel plant biology. Because of the complexity of these techniques, numerous considerations need to be made before embarking on a study. Here we focus on the Arabidopsis model system because of the wealth of available genome-scale data. Many approaches are available that provide genome-scale information regarding the state of a given organism (e.g. genomics, epigenomics, transcriptomics, proteomics, metabolomics interactomics, ionomics, phenomics, etc.). Integration of all of these types of data will be necessary for a comprehensive description of Arabidopsis. In this review we propose that 鈥榯riangulation鈥?among transcriptomics, proteomics and metabolomics is a meaningful approach for beginning this integrative analysis and uncovering a systems level perspective of Arabidopsis biology.