Extraction of glabridin using imidazolium-based ionic liquids

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• 作者：Xueqin Li ; Ruili Guo ; ^{grli@shzu.edu.cn} ; Xiaopeng Zhang ; Xiaoyue Li
• 关键词：Ionic liquids ; Glabridin ; Extraction ; High performance liquid chromatography
• 刊名：Separation and Purification Technology
• 出版年：2012
• 期刊代码：78_13835866
• 类别：ce
• 出版时间：22 March, 2012
• 卷：88
• 期：Complete
• 页码：146-150
• 文件大小：898 K

摘要

The present study aims to extract bioactive glabridin from licorice extract using imidazolium-based ionic liquids (ILs). A series of 1-alkyl-3-methylimidazolium ionic liquids with different anions and alkyl chain lengths of cations were selected to extract glabridin. The results are as follows: IL anions have a significant effect on the extraction efficiency of glabridin, the alkyl chain length of imidazolium cations has a minor effect on the extraction efficiency of glabridin, and IL with [NTf₂]^{鈭?/sup> anion and [C₆mim]+ cation achieve better performances. Under optimal conditions of glabridin extraction technology, a glabridin distribution ratio of 72.67 was achieved with [C₆mim][NTf₂]. The results show that during the extraction, the interactions between IL and glabridin were mainly based on hydrogen-bonding interactions and the hydrophobic interactions.}