Synthesis of carbazoles by dehydro Diels–Alder reactions of ynamides

详细信息	查看全文 | 推荐本文 |

• 作者：M. Fern ; a Martí ; nez-Esperó ; n ; David Rodrí ; guez ; Luis Castedo ; Carlos Saá
• 关键词：DFT ; TDDFT ; TICT ; Michler&#x2019 ; s ketone ; PCM
• 刊名：Tetrahedron
• 出版年：2008
• 期刊代码：107_00404020
• 类别：ch
• 出版时间：21 April 2008
• 卷：64
• 期：17
• 页码：3674-3686
• 文件大小：1161 K

摘要

A new approach to carbazoles and benzannulated carbazoles by means of intramolecular dehydro Diels–Alder of ynamides is reported. N-(o-Ethynyl)aryl ynamides and N-(o-ethynyl) arylynamides were prepared in a few steps starting from o-iodoaniline. Thermal cycloaddition of N-(o-ethynyl)aryl ynamides and N-(o-ethynyl) arylynamides affords carbazoles and benzannulated and heteroannulated carbazoles in moderate-to-good yields.