Catalytic asymmetric carbonylative silylcarbocyclization of enynes
摘要
Rh-, Co- or Ir-promoted cyclization of 1,6-enynes in the presence of a hydrosilane and carbon monoxide leads to the selective formation of functionalized cyclic compounds. Various chiral phosphine type ligands have been used in order to obtain enantiomerically enriched carbocycles. The asymmetric process proceeded with modest enantioselectivities.