• 作者：E. Bravo Ruiz^a ; ^{ebravo2@telefonica.net} ; M. Vega De Cé ; niga^b ; M. Izagirre Loroñ ; o^b ; C. Casco Aguilar^b ; L. Estallo Laliena^b ; Á ; . Barba Vé ; lez^b
• 关键词：Anemia ; Ferropenia ; Par&aacute ; metros nutricionales ; Dé ; ficits nutricionales ; Estado nutricional ; Enfermedad arterial perifé ; rica
• 刊名：Angiolog铆a
• 出版年：2012
• 期刊代码：pca50_00033170
• 类别：med
• 出版时间：May-June, 2012
• 卷：64
• 期：3
• 页码：109-114
• 文件大小：199 K

Introduction

There are very little data on the nutritional status of patients with peripheral arterial disease (PAD). We assessed some nutritional parameters in our PAD patients.

Methods

We retrospectively analysed some nutritional parameters of all patients with PAD diagnosed or followed-up in our centre in 2007-2009 (n = 624). We evaluated serum concentrations of: albumin, total cholesterol, triglycerides, iron, vitamin B12, folic acid, haemoglobin and leucocytes. We compared the parameters according to the severity of the PAD (claudication versus critical ischaemia), gender and age, using square-chi and T-test.

Results

The series included 530 (84.9%) males and 94 (15.1%) females, mean (SD) age 68 (11) (40-94) years, 420 (67.3%) claudicants, and 204(32.7%) critically ischaemic patients (CIP). The prevalence of hypoalbuminaemia, iron deficiency and anaemia was 0.7%(n = 3), 6.7%(n = 28) and 9.8%(n = 41) among claudicants, and 18.1%(n = 37), 31.9%(n = 65) and 49.5%(n = 101) among CIP (P < .0001 for all three). Deficiency of vitamin B12 and folic acid were found in 6.7%(n = 28) and 2.9%(n = 12) of claudicants and 15.7%(n = 32) and 6.4%(n = 13) of CIP (P = .002 and P=.018, respectively). Total cholesterol 鈮?00 mg/dL was more common among CIP (85.3%versus 60.7%; P<.0001), with equal statin intake (43.6%for each group). Deficiency of at least one nutritional parameter was found in 22.4%(n = 94) claudicants in contrast to 71.6%(n = 146) CIP (P<.0001). There were few differences between men and women in both groups, but age increased the prevalence of nutritional deficits, especially lipid concentrations among claudicants, and anaemia in CIP (P < .05).

Conclusions

Nutritional deficiencies are uncommon among claudicants but very prevalent among patients suffering from lower limb critical ischaemia, particularly iron deficiency and anemia. These deficiencies may impair patient recovery and tissue healing. Nutritional assessment in these patients is mandatory in order to offer a complete treatment.