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• 作者：C. Bachmeyer
• 关键词：Jaccoud arthropathy ; Systemic lupus erythematous ; Antiphospholipid syndrome
• 刊名：La Revue de Medecine Interne
• 出版年：2007
• 期刊代码：237_02488663
• 类别：med
• 出版时间：December 2007
• 卷：28
• 期：12
• 页码：871-872
• 文件大小：180 K

摘要

The role of catecholamines in the cardiac expression of pheochromocytoma is well-known. The physiopathology of the syndrome of Tako-tsubo remains more unclear.

Exegesis

We describe 2 clinical cases of acute coronary syndrome with left ventricular dysfunction and no coronary artery stenosis. The first, a syndrome of Tako-tsubo, also known as transient left ventricular apical ballooning syndrome, is characterized by transient wall-motion in the absence of obstructive epicardial coronary disease. The second is a pheochromocytoma with myocardial suffering during hypertension crisis. Through the similarities of these 2 observations, we discuss the physiopathological assumptions to explain the syndrome of Tako-tsubo by underlining the essential place of the catecholamine hypersecretion.

Conclusion

Syndrome of Tako-tsubo and pheochromocytoma are 2 distinct clinical entities. The link between these 2 affections is probably the pathogenic role in cardiac toxicity with the catecholamines.