ANP and BNP in atrial fibrillation before and after cardioversion – and their relationship to cardiac volume and function
- 作者：Susette Krohn Therkelsen ; Bjoern Aaris Groenning ; Andreas Kjaer ; Jesper Hastrup Svendsen ; Gorm Boje Jensen
- 关键词：Atrial fibrillation ; Natriuretic peptides ; Cardiac volume ; Cardioversion ; Magnetic resonance imaging
- 刊名：International Journal of Cardiology
- 出版年：2008
- 期刊代码：128_01675273
- 类别：med
- 出版时间：21 July 2008
- 卷：127
- 期：3
- 页码：396-399
- 文件大小：433 K
摘要
The role of atrial (ANP) and B-type (BNP) natriuretic peptide in atrial fibrillation (AF) is not clear. Our aim was to describe ANP and BNP in AF, and their changes following cardioversion in persistent AF. Furthermore, we wanted to assess the association between ANP and BNP and cardiac volume and function evaluated by magnetic resonance imaging. ANP and BNP decreased significantly following cardioversion. After 180 days of sinus rhythm, ANP and BNP were still significantly elevated. Same results were seen in patients with lone AF. Left and right atrial volumes correlated positively with ANP and BNP. Changes in left atrial volume were predictive of changes in ANP and BNP following cardioversion.