Alternative Smoking Cessation Aids: A Meta-analysis of Randomized Controlled Trials

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• 作者：Mehdi Tahiri ; MD^a ; ^b ; ^c ; Salvatore Mottillo ; MD^a ; ^b ; ^c ; Lawrence Joseph ; PhD^d ; ^e ; Louise Pilote ; MD ; MPH ; PhD^d ; ^e ; ^f ; Mark J. Eisenberg ; MD ; MPH^a ; ^c ; ^d ; ^{mark.eisenberg@mcgill.ca}
• 关键词：Acupuncture ; Alternative smoking cessation aid ; Aversive smoking ; Hypnotherapy ; Meta-analysis ; Smoking cessation
• 刊名：The American Journal of Medicine
• 出版年：2012
• 期刊代码：6_00029343
• 类别：med
• 出版时间：June, 2012
• 卷：125
• 期：6
• 页码：576-584
• 文件大小：424 K

摘要

Background

Acupuncture, hypnotherapy, and aversive smoking are the most frequently studied alternative smoking cessation aids. These aids are often used as alternatives to pharmacotherapies for smoking cessation; however, their efficacy is unclear.

Methods

We carried out a random effect meta-analysis of randomized controlled trials to determine the efficacy of alternative smoking cessation aids. We systematically searched the Cochrane Library, EMBASE, Medline, and PsycINFO databases through December 2010. We only included trials that reported cessation outcomes as point prevalence or continuous abstinence at 6 or 12 months.

Results

Fourteen trials were identified; 6 investigated acupuncture (823 patients); 4 investigated hypnotherapy (273 patients); and 4 investigated aversive smoking (99 patients). The estimated mean treatment effects were acupuncture (odds ratio [OR], 3.53; 95%confidence interval [CI], 1.03-12.07), hypnotherapy (OR, 4.55; 95%CI, 0.98-21.01), and aversive smoking (OR, 4.26; 95%CI, 1.26-14.38).

Conclusion

Our results suggest that acupuncture and hypnotherapy may help smokers quit. Aversive smoking also may help smokers quit; however, there are no recent trials investigating this intervention. More evidence is needed to determine whether alternative interventions are as efficacious as pharmacotherapies.