• 作者：Jesú ; s Tornero Molina^a ; Raimon Sanmartí ; Sala^b ; Vicente Rodrí ; guez Valverde^c ; Emilio Martí ; n Mola^d ; José ; Luis Marenco de la Fuente^e ; Isidoro Gonzá ; lez Á ; lvaro^f ; Santiago Muñ ; oz Ferná ; ndez^g ; Juan G&#243 ; mez-Reino Carnota^h ; Luis Carreñ ; o Pé ; rezⁱ ; Enrique Batlle Gualda^j ; Alejandro Balsa Criado^d ; José ; Luis Andreu^k ; José ; Marí ; a Á ; lvaro-Gracia^f ; Juan Antonio Martí ; nez L&#243 ; pez^f ; ^l ; Estí ; baliz Loza Santamarí ; a^l ; ^{estibaliz.loza@ser.es}
• 关键词：Consenso ; Recomendaciones ; Guí ; as ; Terapias bioló ; gicas ; Artritis reumatoide
• 刊名：Reumatolog铆a Cl铆nica
• 出版年：2010
• 期刊代码：pca303_1699258X
• 类别：med
• 出版时间：January-February 2010
• 卷：6
• 期：1
• 页码：23-36
• 文件大小：249 K

Objective

To provide a reference to rheumatologists and to those involved in the treatment of RA who are using, or about to use biologic therapy.

Methods

Recommendations were developed following a nominal group methodology and based on systematic reviews. The level of evidence and grade of recommendation were classified according to the model proposed by the Center for Evidence Based Medicine at Oxford. The level of agreement was established through Delphi technique.

Results

We have produced recommendations on the use of the seven biologic agents available for RA in our country. The objective of treatment is to achieve the remission of the disease as quickly as possible. Indications and nuances regarding the use of biologic therapy were reviewed as well as the evaluation that should be performed prior to administration and the follow up of patients undergoing this therapy.

Conclusions

We present an update on the SER recommendations for the use of biologic therapy in patients with RA.