• 作者：Juan Ignacio P&#233 ; rez-Calvo^a ; ^{jiperez@unizar.es} ; Jos&#233 ; Luis Morales Rull^b ; Francisco Jos&#233 ; Ruiz Ruiz^a
• 关键词：Cistatina C ; Remodelado card&iacute ; aco ; Remodelado vascular ; Insuficiencia card&iacute ; aca
• 刊名：Medicina Cl铆nica
• 出版年：2011
• 期刊代码：pca254_00257753
• 类别：med
• 出版时间：19 February 2011
• 卷：136
• 期：4
• 页码：158-162
• 文件大小：174 K

Cystatin C (CysC) is an antiprotease useful for measuring kidney function. Beyond such property, it carries significant prognostic information in several fields of cardiovascular diseases. We review data that support CysC as a prognostic factor in cardiovascular diseases among healthy elderly, hypertensive and heart failure patients. In addition, it has been speculated that CysC may be an early marker of ventricular remodelling, primarily involved in its pathogenesis, as a local antiprotease. Its role in physiopathology and clinical issues of cardiovascular pathology is yet to be elucidated.