A review of multiple stressor studies that include ionising radiation

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• 作者：Nathalie Vanhoudt^a ; ^{Nathalie.Vanhoudt@sckcen.be} ; Hildegarde Vandenhove^a ; ^{hvandenh@sckcen.be} ; ^{Hildegarde.Vandenhove@sckcen.be} ; Almudena Real^b ; ^{Almudena.Real@ciemat.es} ; Clare Bradshaw^c ; ^{Clare@ecology.su.se} ; Karolina Stark^c ; ^{Karolina@ecology.su.se}
• 关键词：Multiple stressors ; Radiation ; Risk assessment ; Mixture effects
• 刊名：Environmental Pollution
• 出版年：2012
• 期刊代码：28_02697491
• 类别：env
• 出版时间：September, 2012
• 卷：168
• 期：Complete
• 页码：177-192
• 文件大小：263 K

摘要

Studies were reviewed that investigated the combined effects of ionising radiation and other stressors on non-human biota. The aim was to determine the state of research in this area of science, and determine if a review of the literature might permit a gross generalization as to whether the combined effects of multi-stressors and radiation are fundamentally additive, synergistic or antagonistic. A multiple stressor database was established for different organism groups. Information was collected on species, stressors applied and effects evaluated. Studies were mostly laboratory based and investigated two-component mixtures. Interactions declared positive occurred in 58%of the studies, while 26%found negative interactions. Interactions were dependent on dose/concentration, on organism's life stage and exposure time and differed among endpoints. Except for one study, none of the studies predicted combined effects following Concentration Addition or Independent Action, and hence, no justified conclusions can be made about synergism or antagonism.