Periventricular Leukomalacia is Decreasing in Japan

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• 作者：Tokio Sugiura ; MD ; PhD^a ; ^{tokio@med.nagoya-cu.ac.jp} ; Tatenobu Goto ; MD ; PhD^a ; Hiroko Ueda ; MD^a ; Koichi Ito ; MD ; PhD^a ; Hiroki Kakita ; MD ; PhD^a ; Rika Nagasaki ; MD^a ; Keisuke Mizuno ; MD ; PhD^b ; Satoshi Suzuki ; MD ; PhD^c ; Ineko Kato ; MD ; PhD^a ; Hajime Togari ; MD ; PhD^a
• 刊名：Pediatric Neurology
• 出版年：2012
• 期刊代码：218_08878994
• 类别：med
• 出版时间：July, 2012
• 卷：47
• 期：1
• 页码：35-39
• 文件大小：154 K

摘要

Periventricular leukomalacia is recognized as the leading cause of cerebral palsy in preterm infants. To clarify the prevalence of periventricular leukomalacia and cerebral palsy in Japan, a nationwide survey was performed. The prevalence of periventricular leukomalacia in the group of surviving preterm infants of gestational ages less than 33 weeks born in 2007 was 2.7%(78/2883) on ultrasound diagnosis, and 3.3%(92/2824) on magnetic resonance imaging. The prevalence of cerebral palsy was 4.3%(125/2883) on clinical diagnosis. In our previous study, the prevalences of periventricular leukomalacia in 1990-1991, 1993-1994, 1996, and 1999 were 4.8%, 4.9%, 4.9%, and 5.3%on ultrasound, and 7.9%, 7.7%, 6.9%, and 7.3%on magnetic resonance imaging, respectively. The prevalence of periventricular leukomalacia has decreased significantly in Japan.