Personal observation of skin disorders in malnutrition
- 作者：Benjamin Y. Lee ; Daniel J. Hogan ; Susonne Ursine ; Krishne Yanamandra and Joseph A. Bocchini
- 刊名：Clinics in Dermatology
- 出版年：2006
- 期刊代码：66_0738081x
- 类别：med
- 出版时间：May-June 2006
- 卷：24
- 期：3
- 页码：222-227
- 文件大小：166 K
摘要
This is a description of some unknown skin disorders found by a physician inmate in a concentration camp, 1958 to 1962. After prolonged semistarvation and ultraheavy physical labor, skin lesions developed among the inmates including cutaneous pigmentation overlying bony prominence, buccal membrane pigmentation, palmoplantar keratoderma with fissures, palmar crease clefts, nail layering, intra-nail hemorrhage, and so on. These lesions responded dramatically to nutrition therapy, including dietary improvement, yeast administration, or thiamin injection. Thiamin deficiency was confirmed to be one of major etiologic factors, whereas the deficiency of niacin or riboflavin also played a part. In the pediatric case with palmar crease clefts, both thiamin and niacin were dramatically effective. No laboratory data could be provided.