Impact of Cardiac Transplantation in 24 Hours Circadian Blood Pressure and Heart Rate Profile

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• 作者：Kotsis ; V.T. ; Stabouli ; S.V. ; Pitiriga ; V.Ch. ; Lekakis ; J.P. ; Nanas ; I.N. ; Toumanidis ; S.T. ; et. al.
• 刊名：Transplantation Proceedings
• 出版年：2005
• 期刊代码：252_00411345
• 类别：med
• 出版时间：June, 2005
• 卷：37
• 期：5
• 页码：2244-2246
• 文件大小：107 K

摘要

Objective

The aim of the present study was to evaluate 24 hours blood pressure (BP) and heart rate changes as well as 24-hour circadian BP rhythm of cardiac transplant recipients.

Methods

Twenty-five transplant recipients and twenty-five healthy volunteers underwent 24-hour ambulatory BP monitoring. Parameters of 24-hour ambulatory BP monitoring (24-h/daytime/nightime systolic, diastolic BP, pulse pressure, and heart rate) were determined in all patients.

Results

Clinic systolic/diastolic BP, mean 24-h systolic/diastolic BP, mean daytime systolic/diastolic BP, mean nighttime systolic/diastolic BP, and mean 24-h/daytime/nighttime heart rate were significantly higher in transplant recipients than in control group subjects. Standard deviations of 24-h/daytime/nighttime heart rates were significantly lower in transplant recipients. Dippers were 48%of the control and only 12%of the transplantation group.

Conclusions

Cardiac transplant recipients had increased ambulatory BP. They also had increased 24-h/daytime/nighttime heart rate and decreased heart rate variability. Also, diminished nocturnal decrease of BP was found in transplant recipients.