• 作者：J.I. Martí ; nez-Salamanca^a ; ^{msalamanca99@hotmail.com} ; C. Martí ; nez-Ballesteros^a ; L. Portillo^a ; I. Moncada^b ; J. Carballido^a
• 关键词：C&aacute ; ncer de pr&oacute ; stata ; Prostatectom&iacute ; a radical ; Longitud peneana ; Grosor peneano ; Cambios peneanos ; Disfunci&oacute ; n er&eacute ; ctil ; Calidad de vida
• 刊名：Actas Urol贸gicas Espa帽olas
• 出版年：2010
• 期刊代码：pca37_02104806
• 类别：med
• 出版时间：July-August 2010
• 卷：34
• 期：7
• 页码：579-585
• 文件大小：191 K

class="h4">Introduction

Radical prostatectomy in all its approaches is the treatment of choice for localized prostate cancer and especially in young, sexually active patients with a desire to keep their sex life. In addition to the well-known and defined postoperative erectile dysfunction, erectile silent period causes, in many patients (9鈥?%), structural changes, in the penile structure, sometimes irreversible. These tissue changes, resulting in a loss of length and girth, that concern patients.

class="h4">Objective

To systematically review to date published data in the literature regarding penile changes after radical prostatectomy.

class="h4">Material and methods

We performed a systematic search in: PubMed, EMBASE, Cochrane, SCOPUS, Science Citation Index period January 1990 to September 2009 for the terms 鈥減rostatectomy鈥? 鈥渙rgan size鈥? 鈥渇ibrosis鈥? 鈥渟exual activity鈥? 鈥渆rectile dysfunction鈥? 鈥減enile size鈥? 鈥渞adical prostatectomy鈥? 鈥減rostatic neoplasms鈥? 鈥渂ody weights鈥?and 鈥減enis measures鈥? Seven series of patients were selected for analysis.

class="h4">Results

We described the different measurement methods and their potential biases and differences. Also, we reviewed main physiopathogenic theories to explain this phenomenon. Finally, we detail the results of different series of patients reported.

class="h4">Conclusions

It seems to be a proven fact that the penis undergoes major changes in its length and girth after radical prostatectomy. Several authors have communicated the data of their series and the different treatment options (5PDE inhibitors, vacuum devices, penile extenders, etc.). Strategies addressed to preserve and protect cavernous tissue and tunica albuginea after the procedure, as well as to increase oxygenation and allow erection to be recovered in the shortest posible time positive will impact on the quality of life of our patients.