- 作者：Frances Rice ; Allyson Lewis ; Gordon Harold ; Marianne van den Bree ; Jacky Boivin ; Dale F. Hay ; Michael J. Owen ; Anita Thapar
- 关键词：Reliability ; Prenatal ; Antenatal ; Peri-natal ; Psychiatry ; Psychology ; Child ; Behaviour
- 刊名：Early Human Development
- 出版年：2007
- 期刊代码：82_03783782
- 类别：med
- 出版时间：August 2007
- 卷：83
- 期：8
- 页码：497-504
- 文件大小：201 K
This study aims to assess:
• Pre- and postnatal growth associated with maternal smoking compared to other risk factors for low birth weight.
• The effect of reduction of maternal smoking on growth.
Subjects:
A cohort (n = 269) followed with ultrasound measurements in the third trimester and postnatal anthropometric measurements until 6 months of age. Mothers were interviewed about their smoking habits at 18 and 28 weeks of pregnancy.
Results:
Maternal smoking was associated with a greater reduction in birth length SDS than other causes of equally reduced birth weight (mean difference: − 0.25 SDS, P = 0.013). The adjustment of gestational age, based on bi-parietal diameter at an early dating scan, indicated that mothers who reduced smoking carried smaller fetuses than mothers who continued to smoke heavily (mean difference = 2.6 days, P = 0.012). Birth weights in these two groups were similar (P = 0.87). However at 3 months of age, reduced smoking was associated with lower weight (mean difference = − 0.38 SDS, P = 0.045).
Conclusions:
Maternal smoking was associated with a reduction of linear growth, which was more marked than that of other risk factors, and which seemed to occur before the 3rd trimester. The results indicated a beneficial effect of reduction of smoking upon third trimester growth, and that the decision to reduce smoking in mid-pregnancy may be influenced by early fetal size.