Controlling tuberculosis in a llama (Lama glama) herd using clinical signs, tuberculin skin testing and serology

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• 作者：D.F. Twomey^a ; ^{f.twomey@vla.defra.gsi.gov.uk} ; R. Collins^a ; M.P. Cranwell^a ; T.R. Crawshaw^a ; R.J. Higgins^b ; G.S. Dean^c ; H.M. Vordermeier^c ; A. Hollingdale^d ; R. de la Rua-Domenech^e
• 关键词：Llama (Lama glama) ; Tuberculosis ; Clinical disease ; Tuberculin skin test ; Rapid Test serology
• 刊名：The Veterinary Journal
• 出版年：2012
• 期刊代码：338_10900233
• 类别：med
• 出版时间：May, 2012
• 卷：192
• 期：2
• 页码：246-248
• 文件大小：140 K

摘要

An outbreak of tuberculosis (TB), caused by Mycobacterium bovis, was investigated in a small herd of llamas (Lama glama). Based on three ante-mortem diagnostic methods (clinical signs, tuberculin skin test reactions, and 鈥楻apid Test鈥?serology), 12 llamas were selected for examination post-mortem. Grossly visible lesions suspicious of TB were observed in eight animals, four of which had exhibited clinical signs, one was a skin test 鈥榬eactor鈥? and three had been seropositive. M. bovis was isolated from seven of these eight animals. Clinical signs combined with serology were found to be useful in identifying infected animals, but tuberculin skin testing had limited negative predictive value as four llamas that were subsequently confirmed as infected were not detected using this assay.