Method to perform IV injections on mice using the facial vein

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• 作者：H.B. Levene ; M. Zhang ; C.J. Erb ; J.I. Jallo ; C.M. Loftus ; R.F. Tuma
• 关键词：Murine ; Intravenous injection ; Facial vein ; Spinal cord injury
• 刊名：Journal of Neuroscience Methods
• 出版年：2007
• 期刊代码：33_01650270
• 类别：neu
• 出版时间：30 August 2007
• 卷：164
• 期：2
• 页码：304-307
• 文件大小：827 K

摘要

A novel technique for gaining IV access in a mouse model is presented. Using a cut-down approach, the facial vein is identified through an incision from anterior to the external auditory meatus to posterior to the lateral ispilateral canthus. A small gage needle (30 gauge) may be inserted to inject medications. A high success rate (93%) as determined by direct visualization is achieved. The technique would prove especially useful for animals slated for kinematic testing as the incision does not interfere with the animal's ventral surface.