• 作者：Manuel Ferrer Má ; rquez ; ^{manuferrer78@hotmail.com} ; Á ; ngel Reina Duarte ; Vanesa Maturana Ibá ; ñ ; ez ; Ricardo Belda Lozano ; Francisco Rubio Gil ; Isabel Blesa Sierra ; Marí ; a del Mar Rico Morales
• 关键词：Lynch ; Cá ; ncer colorrectal ; Gené ; tica ; Cirugí ; a
• 刊名：Cirug铆a Espa帽ola
• 出版年：2011
• 期刊代码：pca87_0009739X
• 类别：med
• 出版时间：January 2011
• 卷：89
• 期：1
• 页码：3-9
• 文件大小：312 K

Hereditary nonpolyposis colorectal cancer or Lynch Syndrome, caused by germinal mutations in mismatch deoxyribonucleic acid (DNA) repair genes, is the most common form of hereditary colorectal cancer. The identification of these individuals is not easy and is based on clinical and molecular criteria. A review is presented on the genetics and diagnosis in Lynch Syndrome, as well as on its surgical management and prevention