Copyright © 2007 Elsevier Masson SAS All rights reserved. <h4 class="h4">Cas clinique h4>
Ostxe9;oarthropathie hypertrophiante primitive chez un adolescent
This was mentionned on other family members. The physical examination was otherwise unremarkable. There were no skin thickening, no psoriasis-like and cardio-pulmonary disease features.
These following exams were normal; Hemogram, fibrinogen, C reactive protein, rheumatoxef;d factor, serum calcium and phosphorus, thyroid hormones, growth hormone, chest X-ray, gastroduodenoscopy, electrocardiogram. The skeletal X-ray documented a widespread bone formation, a sacro-iliac osteosclerosis and interosseous ossifications beetwen tibias and fibulas.
Conclusion. – Pachydermoperiostosis diagnosis was set up on 3 out of the 4 Borochowitz criteria. The absence of pachyderma defines this incomplete form. The osteoarticular manifestations lead mainly to differential diagnosis with the secondary hypertrophic osteoarthropathy and chronic inflammatory rheumatisms.
The underlying pathogenic mechanism of this disease remains still unclear.
gn="top" style="padding: 5px 5px 0px 5px"> | href="/science?_ob=ArticleURL&_udi=B6VMG-4K42697-D&_user=10&_origUdi=B6VMG-4R71J8S-1&_fmt=high&_coverDate=09%2F30%2F2006&_rdoc=1&_orig=article&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=b845392fde58b544999596faa59ca2da" onMouseOver="InfoBubble.show('infobubble_3','mlktLink_3')" onMouseOut="InfoBubble.timeout()">Pachydermoperiostose. A propos d'un cas La Revue de Medecine Interne |
ght; padding-left:5px">hide()"> La Revue de Mxe9;decine Interne, Volume 27, Issue 9, September 2006, Pages 710-712 F. Kabi, O. Mkinsi, S. Janani, N. Raissouni Abstract height:150%"><h3 class="h3">Rxe9;sumxe9;h3><h4 class="h4">Introductionh3>La pachydermopxe9;riostose (PDP) ou ostxe9;oarthropathie hypertrophiante (OAH) primitive est une maladie hxe9;rxe9;ditaire rare.<h4 class="h4">Fait cliniqueh3> Nous rapportons une observation de PDP chez un jeune homme de 22 ans, issu d'un mariage consanguin. Le tableau associait une arthropathie, un hippocratisme digital, une pxe9;riostose diffuse et une pachydermie des extrxe9;mitxe9;s et du front. Tout le bilan rxe9;alisxe9; xe0; la recherche d'une xe9;tiologie est restxe9; nxe9;gatif. Ainsi le diagnostic de PDP xe9;tait retenu et le malade xe9;tait traitxe9; par colchicine.<h4 class="h4">Discussionh3> Les problxe8;mes diagnostiques que peut poser la PDP, surtout avec les OAH secondaires et les rhumatismes inflammatoires chroniques sont discutxe9;s.<h4 class="h4">Introductionh3> The pachydermoperiostosis (PDP) or primitive hypertrophic osteoarthropathy (HOA) is a rare hereditary disease.<h4 class="h4">Case recordh3> We report a 22-year-old man born to consanguineous marriage who presented presented with PDP. This patient disclosed an arthropathy, a clubbing, a diffuse periostosis, and a pachyderma of the hands, the feet and the forehead. All the examinations that were performed to look for an etiology remained negative. Diagnosis of PDP was considered and the patient treated with colchicine.<h4 class="h4">Discussionh3> We discuss the diagnostic issues raised by PDP, especially with the secondary HOA and chronic inflammatory rheumatisms. href="http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6VMG-4K42697-D-1&_cdi=6150&_user=10&_orig=article&_coverDate=09%2F30%2F2006&_sk=999729990&view=c&wchp=dGLbVzW-zSkzS&md5=47cb23a92cbd46ddacc5167632bfdf3d&ie=/sdarticle.pdf"> |
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Ostxe9;oarthropathie hypertrophiante primitive chez un adolescent