• 作者：O. Ibarra Barrueta^a ; ^{mariaolatz.ibarrabarrueta@osakidetza.net} ; A. Urrutia Losada^a ; A. Ló ; pez de Torre Querejazu^a ; J. Mayo Suá ; rez^b ; E. Martinez Gutí ; errez^b ; M.J. Martí ; nez-Bengoechea^a
• 关键词：Adherencia ; Terapia antirretroviral ; Sí ; ndrome de la inmunodeficiencia humana adquirida (sida) ; Virus de la inmunodeficiencia humana
• 刊名：Farmacia Hospitalaria
• 出版年：2010
• 期刊代码：pca388_11306343
• 类别：pha
• 出版时间：November-December 2010
• 卷：34
• 期：6
• 页码：279-283
• 文件大小：181 K

Objectives

To evaluate antiretroviral treatment adherence in the HIV patient cohort of our hospital and observe their evolution over a 9-year period; also to determine the individual pattern of adherence over time.

Methods

Descriptive study of the evolution of average annual adherence and the annual percentage of adherent patients greater than 95%from 2000 to 2008. We analysed the individual pattern of adherence over time and patients were classified into consistently adherent, consistently non-adherent, and fluctuating.

Results

In the analysis of 577 patients, baseline adherence was significantly greater in na茂ve patients with respect to those who were pre-treated.

Average annual adherence increased slightly and stayed at values around 95%. As with the percentage of patients with adherence greater than 95%, which increased from 64%in 2000 to 79%in 2008.

In terms of the individual pattern of adherence over time, of the 468 patients analysed, the majority (59%) were consistently adherent, 4%non-adherent, and the rest (37%) fluctuated in their adherence.

Conclusions

In our cohort the overall adherence values maintained themselves over time and even show a positive trend, likely the result of systematic monitoring of adherence and implementation strategies to maintain adherence.