Distinct effects of attention and affect on pain perception and somatosensory evoked potentials

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• 作者：Ramona Kenntner-Mabiala ; Marta Andreatta ; Matthias J. Wieser ; Andreas Mü ; hlberger ; Paul Pauli
• 关键词：Affect ; Attention ; Electrical stimuli ; Emotion ; Pain ; Somatosensory evoked potentials
• 刊名：Biological Psychology
• 出版年：2008
• 期刊代码：6_03010511
• 类别：neu
• 出版时间：April 2008
• 卷：78
• 期：1
• 页码：114-122
• 文件大小：496 K

摘要

We applied laser heat stimuli below and above pain threshold to 16 paid volunteers. LEPs were recorded from 60 electrodes during stimulation of the left hand. The two major LEP components were a negative peak at 210 ms (N210) and a positive peak with a mean latency of 350 ms (P350). Furthermore, in some but not in all Ss we found an earlier negative component (N150). The data were used for source location of these LEP components using the boundary element method (BEM). A three-dimensional head coordinate system was created with a 3D digitizer in order to overlay the functional LEP data to the MRI.

Single equivalent dipole analysis showed that the sources of the N150 component could be found in the primary somatosensory cortex contralaterally to the stimulated hand. The dipole localizations of the later components were not as clear as for the N150. However using PET localizations from other laboratories as constraints we were able to localize this components, too. This localizations will be interpreted in the light of multidimensional approaches to pain.