Genomic salmon testes DNA as a catalyst for Michael reactions in water

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• 作者：Margherita De Rosa^a ; Sara Di Marino^b ; Anna Maria D&rsquo ; Ursi^b ; Maria Strianese^a ; Annunziata Soriente^a ; ^{titti@unisa.it}
• 关键词：Catalysis ; DNA ; Water ; Michael addition ; Fluorescence spectrometry
• 刊名：Tetrahedron
• 出版年：2012
• 期刊代码：107_00404020
• 类别：ch
• 出版时间：8 April, 2012
• 卷：68
• 期：14
• 页码：3086-3091
• 文件大小：962 K

摘要

The DNA molecule, recognized as the carrier of genetic information in聽vivo, can function as an efficient organocatalyst for Michael additions of 1,3-dicarbonyl compounds to activated alkenes in aqueous media. The procedure described here is environmentally benign and offers several advantages in terms of simplicity, generality and efficiency. We have used fluorescence spectroscopy to evaluate the catalytic activity of a molecule of DNA.