An electrochemically enhanced solid-phase microextraction approach based on molecularly imprinted polypyrrole/multi-walled carbon nanotubes composite coating for selective extraction of fluoroquinolones in aqueous samples

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• 作者：Xue Liu^a ; Xiaochun Wang^b ; Feng Tan^a ; ^{tanfdl@yahoo.com.cn} ; Hongxia Zhao^a ; Xie Quan^a ; Jingwen Chen^a ; Lianjun Li^a
• 关键词：EC-SPME ; electrochemically controlled solid-phase microextraction ; EE-SPME ; electrochemically enhanced solid-phase microextraction ; MIPPy/MWCNTs ; molecularly imprinted polypyrrole/multi-walled carbon nanotubes ; NIPPy/MWCNTs ; nonimprinted polypyrrole/multi
• 刊名：Analytica Chimica Acta
• 出版年：2012
• 期刊代码：2_00032670
• 类别：ch
• 出版时间：21 May, 2012
• 卷：727
• 期：Complete
• 页码：26-33
• 文件大小：925 K

摘要

In this study, an electrochemically enhanced solid-phase microextraction (EE-SPME) approach based on molecularly imprinted polypyrrole/multi-walled carbon nanotubes (MIPPy/MWCNTs) composite coating on Pt wire was developed for selective extraction of fluoroquinolone antibiotics (FQs) in aqueous samples. During the extraction, a direct current potential was applied to the MIPPy/MWCNTs/Pt fiber as working electrode in a standard three-electrode system, FQ ions suffered electrophoretic transfer to the coating surface and then entered into the shape-complimentary cavities by hydrogen-bonding and ion-exchange interactions. After EE-SPME extraction, the fiber was desorbed with desorption solvent for high-performance liquid chromatography (HPLC) analysis. Some parameters influencing EE-SPME extraction such as applied potential, extraction time, solution pH, ionic strength, and desorption solvent were optimized. EE-SPME showed good selectivity and higher extraction efficiency to FQs compared with that of traditional solid-phase microextraction. EE-SPME coupled with HPLC to determine FQs in water samples, the limits of detection (S/N = 3) for the selected FQs are 0.5-1.9 渭g L^鈭?. The proposed method was successfully used to the analysis of FQs spiked urine and soil samples, with recoveries of 85.1-94.2%for the urine samples and 89.8-95.5%for the soil samples.