Analysis of selected poppy (Papaver somniferum L.) cultivars: Pharmaceutically important alkaloids

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• 作者：Irena Stranska ; Milan Skalicky ; ^{skalicky@af.czu.cz} ; Jan Novak ; Elena Matyasova ; Vaclav Hejnak
• 关键词：Papaver somniferum ; Morphine ; Codeine ; Thebaine ; Papaverine ; Narcotine ; Cultivars
• 刊名：Industrial Crops and Products
• 出版年：2013
• 期刊代码：56_09266690
• 类别：abs
• 出版时间：January, 2013
• 卷：41
• 期：Complete
• 页码：120-126
• 文件大小：343 K

摘要

The content of pharmaceutically important alkaloids (morphine, codeine, thebaine, papaverine and narcotine) was analysed in the empty poppy capsules (poppy straw) of fifteen selected cultivars of Papaver somniferum. By applying the cluster analysis and k-means methods, four clusters representing the sets of cultivars with a defined level of production of the selected alkaloids were determined, based on their similarities.

The content of individual minor alkaloids, which was obtained was relatively low (0.00-0.17%) and in some cases negligible, defined by the dominant representation of morphine in the alkaloid spectrum of all selected cultivars. In addition to the high-morphine cultivar 鈥楤uddha鈥?(mean 1.64%), there was a middle content (mean 0.79%) or low content (mean 0.61%) of morphine in the cultivars included in clusters 2 and 3 (average of 3 consecutive years 2007, 2008 and 2009). A relatively high content of morphine was detected in cultivar 鈥楤枚hm暖v b臎losemenn媒鈥?(mean 0.91%), although it is usually published that white-seed cultivars contain less morphine and other alkaloids, compared to blue-seed or grey-seed cultivars. Low content of morphine (mean 0.48%resp. 0.44%) by relatively high content of narcotine (mean 0.11%resp. 0.15%) was obtained in poppy cultivars 鈥楧anneborg鈥?and 鈥楾atarstan鈥? Also, surprisingly the highest papaverine content (mean 0.07%) was detected in the cultivar 鈥楽u拧ick媒 膷ervenosemenn媒鈥?with the lowest content of morphine (mean 0.34%).