Gold(III) chloride (HAuCl₄路3H₂O) in PEG: A new and efficient catalytic system for the synthesis of functionalized spirochromenes

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• 作者：Mazaahir Kidwaip>1p>p> ; p>p>kidwai.chemistry@gmail.comp> ; Anwar Jahan ; Neeraj Kumar Mishra
• 关键词：Multicomponent reaction (MCR) ; Isatins or Acenaphthoquinone ; Active methylene compounds ; Cyclic 1 ; 3-diketones ; Gold(III) chloride (HAuCl4· ; 3H2O) ; Polyethylene glycol (PEG) ; Spirochromenes
• 刊名：Applied Catalysis A ; General
• 出版年：2012
• 期刊代码：4_0926860x
• 类别：ch
• 出版时间：28 May, 2012
• 卷：425-426
• 期：Complete
• 页码：35-43
• 文件大小：946 K

摘要

Gold(III) chloride (HAuCl₄路3H₂O) in PEG 400 was found to be an efficient catalytic system for the synthesis of biologically important functionalized spirochromene derivatives via one-pot three-component reaction of isatins/acenaphthoquinone, active methylene compounds and cyclic 1,3-diketones/4-hydroxycoumarin. A new catalytic system, recyclability of reaction medium, little reaction times and excellent yields with easy workup render this protocol more attractive and economically viable.