An antagonist of lipid A action in mammals has complex effects on lipid A induction of defence responses in the model plant Arabidopsis thaliana
- 作者：Gitte Erbs ; Tina T ; rup Jensen ; Alba Silipo ; William Grant ; J. Maxwell Dow ; Antonio Molinaro ; Michelangelo Parrilli ; Mari-Anne Newman
- 关键词：PAMPs ; Halomonas magadiensis ; Lipid A ; Antagonist ; Arabidopsis thaliana
- 刊名：Microbes and Infection
- 出版年：2008
- 期刊代码：65_12864579
- 类别：imm
- 出版时间：April 2008
- 卷：10
- 期：5
- 页码：571-574
- 文件大小：152 K
摘要
Lipopolysaccharides, the ubiquitous part of the outer membrane of Gram-negative bacteria, and their derivatives are recognised by plants to trigger or potentiate particular defence responses such as induction of genes encoding pathogenesis-related proteins. The molecular mechanisms of LPS perception that underpin these effects in plants are, however, unknown. Here, lipid A from Halomonas magadiensis, which is an antagonist of lipid A action in human cells, was used to investigate lipid A action in plants. Our findings offer an insight into the different structural requirements for direct induction and potentiation of plant defences by lipid A.