Eficacia de la monitorizaci贸n videoelectroencefalogr谩fica prolongada con protocolo espec铆fico de activaci贸n cerebral en el diagn贸stico diferencial de la epilepsia
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摘要

Objective

To analyze the usefulness of a specific EEG activation protocol during video-EEG (VEEG) monitoring in the differential diagnosis of epilepsy.

Method

Since January 2009, 181 patients underwent two different EEG activation protocols during VEEG monitoring in the Epilepsy Unit of Hospital Ruber International. One protocol (the 鈥渟tandard protocol鈥? included hyperventilation and intermittent photo-stimulation while the other (鈥渟pecific protocol鈥? consisted of potentially provocative cognitive tasks (reading, writing, calculation and spatial construction). Both protocols where supervised by specialized epilepsy nurses, who assessed the correct performance of these activation tasks.

Results

After applying the two protocols during VEEG monitoring a diagnosis of focal epilepsy (FE) was achieved in 144 out of 181 patients and idiopathic generalized epilepsy (IGE) in 37 out of 181. The specific activation protocol induced epileptiform activity (EA) or seizures in 34 out of 37 patients in the IGE group and in none in the FE group. Fifteen of our IGE patients had a wrong diagnosis of FE before being evaluated with VEEG using the specific protocol, and the wrong diagnoses could be corrected after the study. In three patients of the IGE group the VEEG was normal.

Conclusions

Our results suggest that the application of these specific activation techniques that included cognitive tasks is a simple and useful tool in the diagnosis of epilepsy.

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