• 作者：M. Gomez Duque^a ; C. Enciso Olivera^b ; E. Peñ ; a Torres^c ; O.D. Segura Durá ; n^d ; V.H. Nieto Estrada^e ; ^{victorhugonieto@aol.com}
• 关键词：Isquemia miocá ; rdica ; Electrocardiografí ; a ambulatoria ; Sepsis ; Choque sé ; ptico
• 刊名：Medicina Intensiva
• 出版年：2012
• 期刊代码：pca255_02105691
• 类别：med
• 出版时间：June-July, 2012
• 卷：36
• 期：5
• 页码：343-350
• 文件大小：204 K

Objective

To describe the incidence of cardiovascular adverse events in patients with sepsis in its various stages.

Design

A longitudinal, descriptive, observational study was carried out.

Setting

Intensive care units of two university hospitals in Bogot谩 (Colombia).

Patients

A number of patients consecutively admitted to the adult ICU with a diagnosis of sepsis, and no evidence of previous ischemic myocardial injury.

Interventions

Forty-eight hours of electrocardiographic record using Holter technology.

Main variables

Ischemia, cardiac arrhythmia, heart rate variability.

Results

A total of 100 patients were analyzed, 62%being staged as presenting septic shock. Three percent suffered ischemic events detected by Holter and unnoticed through conventional monitoring. Forty-six percent suffered an arrhythmic event detected by Holter, compared with only 6%as detected by conventional monitoring. Mortality was 40%. All patients showed loss of heart rate variability.

Conclusion

In this study patients with sepsis showed a low incidence of cardiovascular ischemic events. In contrast, arrhythmic events showed a high incidence. Conventional monitoring failed to detect any of the ischemic events and most arrhythmic events. In this study, cardiovascular events generated by adrenergic discharge had no impact upon mortality.