- 作者：Jesú ; s Marí ; a Villar Del Moral<sup>asup><sup> ; sup><sup>jevillarmo@yahoo.essup> ; Nuria Muñ ; oz Pé ; rez<sup>asup> ; Antonio Rodrí ; guez Ferná ; ndez<sup>bsup> ; Erika Olmos Juá ; rez<sup>asup> ; Clotilde Moreno Corté ; s<sup>asup> ; Rubé ; n Rodrí ; guez Gonzá ; lez<sup>asup> ; Francisco Javier Martí ; n Cano<sup>asup> ; Rocí ; o Sá ; nchez Sá ; nchez<sup>bsup> ; José ; Antonio Ferró ; n Orihuela<sup>asup>
- 关键词：Glá ; ndulas suprarrenales ; Tumores de las glá ; ndulas suprarrenales ; Tomografí ; a por emisió ; n de positrones ; Pruebas diagnó ; sticas ; Sensibilidad ; Especificidad ; Valor predictivo positivo ; Valor predictivo negativo
- 刊名：Cirug铆a Espa帽ola
- 出版年：2010
- 期刊代码：pca87_0009739X
- 类别：med
- 出版时间：October 2010
- 卷：88
- 期：4
- 页码：247-252
- 文件大小：180 K
ss="h4">Introduction
The usefulness of 18fluorodeoxyglucose positron emission tomography combined with axial tomography (PET-CT) in diagnosing whether adrenal tumours are benign or malignant is assessed.
ss="h4">Material and methods
A retrospective study conducted between June 2005 and May 2009 on a consecutive series of patients on whom a PET-CT scan was performed to study suspected malignant adrenal disease. Focal uptakes were assessed, along with the maximum standard uptake value (SUV), and the ratio of the maximum adrenal/hepatic value. The sensitivity, specificity, positive and negative predictive value of the test, the maximum adrenal uptake values and the ratio for those where the diagnostic yield was maximum.
ss="h4">Results
Fifteen patients were included. The final diagnosis showed malignancy in eight and seven were benign. Ten patients had adrenal uptake: three in benign lesions and seven in neoplasias, with a mean uptake value of 6.3 (3.2 in benign lesions and 9.0 in malignant lesions). The mean adrenal/hepatic ratio was 1.8 (0.9 in benign and 2.6 in malignant lesions). When the presence of adrenal uptake is associated with a final diagnosis of malignancy, we obtained a sensitivity of 87.5%, a specificity of 57.1%, and a positive and negative predictive value of 70%and 80%, respectively. An SUV cut-off value of 6, or an adrenal/hepatic uptake ratio of 2, gave a sensitivity of 75%, a specificity of 100%, and a positive and negative predictive value of 100%and 77.7%, respectively.
ss="h4">Conclusions
PET-CT has a high ability to discriminate between benign and malignant lesions in the adrenal disease studied.