- 作者：J. Morin ; B. Chavent ; chavent.bertrand@hotmail.fr ; A. Duprey ; J.N. Albertini ; J.P. Favre ; X. Barral
- 关键词：Solitary kidney ; Autotransplantation ; Dysplasia ; Renal artery aneurysm ; Ex-vivo repair
- 刊名：European Journal of Vascular and Endovascular Surgery
- 出版年：2012
- 期刊代码：122_10785884
- 类别：med
- 出版时间：June, 2012
- 卷：43
- 期：6
- 页码：716-720
- 文件大小：465 K
Introduction
Autotransplantation of a solitary kidney provides an excellent opportunity to study the immediate and long-term consequences of intra-operative renal ischaemia. The purpose of this report is to describe a series of nine patients who underwent ex聽vivo repair and autotransplantation on solitary kidneys.Patients and methods
The series included six females and three males with a mean age of 36 years. Seven of the nine patients were hypertensive (mean number of anti-hypertensive agents: 3). Two patients had chronic renal failure (serum creatinine levels: 192 and 205聽渭mol聽l鈭?). All arteries except one with Takayasu disease were affected by dysplastic aneurysm or fibrodysplasia lesion. There was no atherosclerotic lesion. The mean number of renal artery branches repaired was 3.1 per patient. Mean duration of ischaemia was 161聽min.
Results
Creatinaemia increased in all patients following the procedure. Creatinaemia and clearance returned to preoperative values between the 3rd and 10th postoperative days. One kidney was lost due to renal vein thrombosis. Late findings indicated that renal function was stable and there was no deterioration in the function of the autotransplanted kidneys after a follow-up period of 89 months. Preoperative versus postoperative creatinaemia and clearance levels were respectively 111 vs. 105聽渭mol聽l鈭? and 66.9 vs. 62.0聽ml聽min鈭? (ns). During the same time, the mean number of anti-hypertensive agents decreased slightly from 3 to 2.5.
Conclusion
In this small series of patients who underwent ex聽vivo repair and autotransplantation on solitary kidneys, intra-operative renal ischaemia had no detrimental effect on renal function.