Evaluation of ActiTrac® (ambulatory activity monitor) in Parkinson's Disease
- 作者：Pedro J. Garcia Ruiz ; Vicenta Sanchez Bernardos
- 关键词：Parkinson's disease ; Ambulatory activity monitor
- 刊名：Journal of the Neurological Sciences
- 出版年：2008
- 期刊代码：178_0022510x
- 类别：med
- 出版时间：15 July 2008
- 卷：270
- 期：1-2
- 页码：67-69
- 文件大小：189 K
摘要
At present, the evaluation of Parkinson's Disease (PD) relies mainly on Unified Parkinson's Disease Rating Scale (UPDRS). Other objective measures have been proposed, including functional studies, timed tests and ambulatory activity monitors (AAM). We carried out a prospective study to analyze the utility and correlation of the AAM: ActiTrac® with UPDRS scores and timed tests in patients with PD. We studied 28 patients with idiopathic PD (age: 62 ± 11years; duration of illness: 7.7 ± 4.4years; clinical stage 2.3 ± 0.39). Motor evaluation included UPDRS and five timed tests: Purdue Pegboard test and those proposed in CAPIT protocol, pronation–supination (PS), finger dexterity (FD), movement between two points (MTP) and walking test (WT). Clinical evaluation was performed in off condition, at 9 a.m., (12h off their medication). Finally, ActiTrac® was placed on the wrist (more affected side) continuously for at least 72h. ActiTrac® activity was correlated (Spearman) with total UPDRS (r: − 0.53, p < 0.005) and motor UPDRS (r:− 0.46, p: 0.01); UPDRS rigidity subscore (r:− 0.52, p < 0.01); UPDRS bradykinesia subscore (r:− 0.48; p:0.01); FD (r: − 0.47 p: 0.01), WT (r: − 0.49, p < 0.01) and Purdue test (r:0.54; p < 0.01). ActiTrac® seems to be a reasonably accurate method to evaluate motor activity in PD.