Nonenhanced ECG-gated quiescent-interval single-shot MRA (QISS-MRA) of the lower extremities: Comparison with contrast-enhanced MRA

详细信息	查看全文 | 推荐本文 |

• 作者：J. Klasen^a ; D. Blondin^a ; ^{blondin@med.uni-duesseldorf.de} ; P. Schmitt^b ; X. Bi^c ; R. Sansone^d ; H.-J. Wittsack^a ; P. Krö ; pil^a ; M. Quentin^a ; J. Kuhlemann^a ; F. Miese^a ; C. Heiss^d ; M. Kelm^d ; G. Antoch^a ; R.S. Lanzman^a
• 刊名：Clinical Radiology
• 出版年：2012
• 期刊代码：282_00099260
• 类别：med
• 出版时间：May, 2012
• 卷：67
• 期：5
• 页码：441-446
• 文件大小：564 K

摘要

| Figures/TablesFigures/Tables | ReferencesReferences

Aim

To evaluate electrocardiogram (ECG)-gated quiescent-interval single-shot magnetic resonance angiography (QISS-MRA) for nonenhanced assessment of peripheral artery occlusive disease (PAOD) using contrast-enhanced MRA (CE-MRA) as the reference standard.

Materials and methods

Twenty-seven patients (mean age 66.6聽卤聽10.8 years) with PAOD were included in the study. QISS-MRA and CE-MRA of the lower extremity were performed using a 1.5 T MR scanner. In each patient, subjective image quality and the degree of stenosis were evaluated on a four-point scale for 15 predefined arterial segments.

Results

Twenty-five of the 27 patients were considered for analysis. Subjective image quality of QISS-MRA was significantly lower for the distal aorta, pelvic arteries, and femoral arteries as compared to CE-MRA (p聽<聽0.01), while no significant difference was found for other vascular segments. The degree of stenosis was overestimated with QISS-MRA in 23 of 365 (6.3%) segments and underestimated in two of 365 (0.5%) segments. As compared to CE-MRA, QISS-MRA had a high sensitivity (98.6%), specificity (96%) as well as positive and negative predictive value (88.7 and 99.6%, respectively) for the detection of significant stenosis (鈮?0%).

Conclusion

ECG-gated QISS-MRA is a promising imaging technique for reliable assessment of PAOD without the use of contrast material.