- 作者：Amparo Arroyo Ferná ; ndez ; amparo.arroyo@xij.gencat.net ; Agustí ; Mora Font ; Marta Sá ; nchez Fité ; Marí ; a Barbal Pagé ; s ; Mariona Palahí ; Adroher
- 关键词：Drogas de abuso ; Aná ; lisis de saliva ; Medicina legal
- 刊名：Revista Espa帽ola de Medicina Legal
- 出版年：2008
- 期刊代码：pca314_03774732
- 类别：med
- 出版时间：2008
- 卷：34
- 期：1
- 页码：3-10
- 文件大小：323 K
Introduction
In legal medicine the study of the detection of drugs of abuse is interesting in different fields. In the vehicles conduction field takes special importance for the social and legal repercussion that supposes driving under the effects of the drugs. Nowadays the saliva is not an invasive sample that has demonstrated its usefulness for the analysis of drugs of abuse.
Objectives
To obtain information about consumption of drugs of abuse in saliva of drivers, neither offenders nor injured, in a recreational area. To evaluate the physical alterations on suspicious people under the influence of drugs of abuse. To check the legal regulation on driving and drugs of abuse.
Material and methods
Transversal observational study. Size of the sample: 632 samples of saliva from drivers collected by policemen in Catalonia, Spain. Screening of drugs of abuse in saliva through of immunoassay test (Cozart庐 kit). Drugs detected by the test are: cocaine, cannabis (螖9-tetrahydrocannabinol), opiates (6-monoacetilmorphine) amphetamine, and metamphetamine. Confirmation of positive results by Gas Chromatography-Mass Spectrometry (GC-MS).
Results
82%of positive results were obtained. 62. 3%were positive for 1 drug, 29.8%for 2 drugs, and 7.8%for 3 or more drugs. Considered isolated each one, the prevalence of cannabis was 48.4%and 49. 3%for cocaine, 1.54%, for opiates, and amphetamines and methamphetamines, 0.61%. The combination of 2 drugs was positive for 83.2%of the sample. The most common combination was cocaine and cannabis.
Conclusions
A high prevalence of consumption of drugs was observed in the population studied. The study provides interesting information on the driver samples. The association between psychophysic changes and drug consumption is not well established with the method used. Nowadays, legal issues related to driving under the influence of the drugs are being developed.