Synthesis of pillar[7]arene

详细信息	查看全文 | 推荐本文 |

• 作者：Yu Chen^a ; Hong Qi Tao^a ; Yu Hui Kou^a ; Herbert Meier^b ; Jian Long Fu^a ; De Rong Cao^a ; ^{drcao@scut.edu.cn}
• 关键词：Pillar[n]arenes ; Pillar[7]arene ; Host&ndash ; guest chemistry ; Condensation reaction ; Iron(III) chloride
• 刊名：Chinese Chemical Letters
• 出版年：2012
• 期刊代码：3_10018417
• 类别：ch
• 出版时间：May, 2012
• 卷：23
• 期：5
• 页码：509-511
• 文件大小：174 K

摘要

The first synthesis of pillar[7]arene is reported with two methods. Method A: the FeCl₃-catalyzed condensation reaction of 1,4-dimethoxybenzene (1) with paraformaldehyde in CHCl₃ gave dimethoxypillar[7]arene (3). Method B: the <em>pem>-toluenesulfonic acid catalyzed condensation reaction of 2,5-bis(benzyloxymethyl)-1,4-dimethoxybenzene (2) in CH₂Cl₂ gave compound 3. Demethylation of 3 with BBr₃ gave pillar[7]arene (4). The pillar[7]arene might be a perspective macrocyclic host in host-guest chemistry.