In a randomized, dou
ble-
blind, placebo-controlled clinical trial, the plaque volumes in both carotid and femoral arteries of 152 probationers were determined by B-mode ultrasound. Continuous intake of high-dose garlic powder dragées reduced significantly the increase in arteriosclerotic plaque volume by 5–18%or even effected a slight regression within the observational period of 48 months. Also the age-dependent representation of the plaque volume shows an increase between 50 and 80 years that is diminished under garlic treatment by 6–13%related to 4 years. It seems even more important that with garlic application the plaque volume in the whole collective remained practically constant within the age-span of 50–80 years. These results substantiated that not only a preventive but possi
bly also a curative role in arteriosclerosis therapy (plaque regression) may be ascribed to garlic remedies.
black"> Publisher: | black"> Elsevier Science |
black"> Language of Publication: | black"> English |
black"> Item Identifier: | black"> S0021-9150(99)00060-X |
black"> Publication Type: | black"> Article |
black"> ISSN: | black"> 0021-9150 |
black"> Cited by: | black"> - Gardner, Christopher D.; Chatterjee, Lorraine M.; Carlson, Joseph J.,"The effect of a garlic preparation on plasma lipid levels in moderately hypercholesterolemic adults"Atherosclerosis2001pp. 213-220
Bibliographic PageFull Text - Bast, Aalt; Chandler, R. Frank; Choy, Patrick C.; Delmulle, Luc M.; Gruenwald, Joerg; Halkes, S. Bart A.; Keller, Konstantin; Koeman, Jan H.; Peters, Paul; Przyrembel, Hildegard; de Ree, Ellen M.; Renwick, Andrew G.; Vermeer, Ingrid T.M.,"Botanical health products, positioning and requirements for effective and safe use1"Environmental Toxicology and Pharmacology2002pp. 195-211
Bibliographic PageFull Text |
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| black"> Footnotes: Correspondence to: Nicole G.C. Wevers, ETAF, European Training and Assessment Foundation, PO Box 182, 6700 AD, Wageningen, The Netherlands. Tel.: +31-317-450202; fax: +31-317-351173.
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