S-(-)-ET 126: A potent and selective M₁ antagonist in vitro and in vivo

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• 作者：Ghelardini ; Carla ; Bartolini ; Alessandro ; Galeotti ; Nicoletta ; Teodori ; Elisabetta ; Gualtieri ; Fulvio
• 关键词：S-(-)-ET 126 ; M₁ selective muscarinic antagonist ; M₁ ; M₂ and M₃ subtype ; analgesia
• 刊名：Life Sciences
• 出版年：1996
• 期刊代码：62_00243205
• 类别：imm
• 出版时间：February 16, 1996
• 卷：58
• 期：12
• 页码：991-1000
• 文件大小：460 K

摘要

The pharmacological profile of the competitive muscarinic antagonist S-(-)-α-(hydroxymethyl)benzeneacetic acid 1-methyl-4-piperidinyl ester (S-(-)-ET 126) was evaluated on M₁ (rabbit vas deferens; pA₂