• 作者：Helen De Nobrega-Correa ; Mery Guerra-Velá ; squez ; Eduardo Reyna-Villasmil ; ^{sippenbauch@gmail.com} ; Jorly Mejia-Montilla ; Nadia Reyna-Villasmil ; Duly Torres-Cepeda ; Joel Santos-Bolí ; var ; Juan Perozo-Romero
• 关键词：Hioscina ; Oxitocina ; Parto ; Embarazo a té ; rmino
• 刊名：Progresos de Obstetricia y Ginecolog铆a
• 出版年：2010
• 期刊代码：pca294_03045013
• 类别：med
• 出版时间：December 2010
• 卷：53
• 期：12
• 页码：502-506
• 文件大小：119 K

Objective

To compare the effects of intravenous hyoscine butylbromide-oxytocin or oxytocin on the duration of labor in term pregnancies.

Method

Ninety patients were selected and randomly assigned to receive intravenous hyoscine butylbromide-oxytocin (n = 45) or intravenous oxytocin (n = 45). We evaluated maternal adverse effects, effects on neonatal Apgar score, cervical dilatation 1 hour after drug administration and the interval between the onset of labor and delivery.

Results

There were no significant differences between the two groups in maternal age, gestational age, or Bishop score at drug administration (p = ns). No significant differences were observed in the duration of the first, second or third phases of labor between the two groups (p = ns). No significant differences were found between the groups in Apgar scores at 1 and 5 minutes (p = ns). No maternal adverse effects were observed or reported due to the use of hyoscine-butylbromide or oxytocin.

Conclusion

The effect of hyoscine butylbromide-oxytocin on the duration of labour in term pregnancies is similar to that of oxytocin. The drug does not alter Apgar score or produce maternal adverse effects.