To compare serum homocysteine concentrations in the newborns of preeclamptic patients and normotensive pregnant women.
Thirty-five preeclamptic patients and their newborns (group A; cases) and 35 normotensive pregnant women and their newborns (group B; controls) were selected. Maternal-neonatal homocysteine concentrations and neonatal weight were evaluated in both groups.
Statistically significant differences were found in gestational age, systolic and diastolic blood pressure and the presence of proteinuria (p<0.05). Maternal homocysteine concentrations were higher in group A than in group B (p<0.05). Mean neonatal weight was significantly lower in group A than in group B (p<0.05). Neonatal homocysteine concentrations were higher in group A than in group B (p<0.05). When the homocysteine concentrations of newborns were correlated, there was a moderate, positive and significant correlation with maternal homocysteine concentrations and a moderate, negative and significant correlation with neonatal weight (p<0.05).
Homocysteine concentrations were significantly higher in the newborns of preeclamptic patients than in those of normotensive pregnant women.