Metabolic effects of implantable steroid contraceptives for women

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• 作者：Dorflinger ; Laneta J.
• 关键词：Metabolism ; Implants ; Norplant ; Jadelle ; Implanon ; Uniplant ; Surplant ; Elcometrine ; Nestorone ; Sino-Implant ; Levonorgestrel ; Etonogestrel ; Nomegestrol acetate ; ST-1435
• 刊名：Contraception
• 出版年：2002
• 期刊代码：71_00107824
• 类别：med
• 出版时间：January, 2002
• 卷：65
• 期：1
• 页码：47-62
• 文件大小：117 K

摘要

The metabolic impact of progestin-only contraceptives is less than that of combined oral contraceptives. Subdermal contraceptive implant systems that provide a sustained release of low levels of progestins are now becoming widely available. This review evaluates the metabolic effects of currently available products that release the progestins levonorgestrel (Norplant, Jadelle, and their Chinese equivalents); etonogestrel (Implanon); nomegestrol acetate (Uniplant); and Nestorone, formally called ST-1435 (Nestorone implant/Elcometrine). Data on liver, kidney, and renal function; carbohydrates and insulin release; hemostasis; blood pressure; and lipids are considered.