The combined contraceptive ring NuvaRing® and spermicide co-medication

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• 作者：Haring ; T. ; Mulders ; T.M.T.
• 关键词：Vaginal ring ; Contraceptive ; Nonoxynol-9 ; Drug interaction ; Spermicide
• 刊名：Contraception
• 出版年：2003
• 期刊代码：71_00107824
• 类别：med
• 出版时间：April, 2003
• 卷：67
• 期：4
• 页码：271-272
• 文件大小：35.7 K

摘要

The effects of nonoxynol-9 on etonogestrel and ethinylestradiol release and absorption from NuvaRing® were studied in 12 subjects for two cycles: one control and one interaction cycle (nonoxynol-9 was administered on day 8). Nonoxynol-9 had no effect on release or absorption and, consequently, serum levels. Therefore, nonoxynol-9 did not compromise the contraceptive efficacy of NuvaRing.